Simultaneous voltammetric determination of nitazoxanide and ofloxacin in pharmaceutical formulation
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منابع مشابه
Simultaneous Voltammetric Determination of Nitazoxanide and Ofloxacin in Pharmaceutical Formulation
A simple, sensitive and highly selective electrochemical method was developed for the simultaneous determination of nitazoxanide and ofloxacin in aqueous media (Britton-Robinson buffer, pH-8.36) on a hanging mercury drop electrode (HMDE) using differential pulse polarography (DPP). Using DPP a separation of about 936 mV between the peak oxidation potentials of nitazoxanide and ofloxacin present...
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Two simple, selective, rapid, precise and economical reverse phase high-pressure liquid chromatography methods have been developed; first method for estimation of nitazoxanide and second method for simultaneous estimation of nitazoxanide & ofloxacin from pharmaceutical dosage forms. The first method carried out on a Hypersil BDS C8 column (5μ particles size) (250 mm X 4.6 mm), with mobile phase...
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Voltamogramas cíclicos de nitazoxanida medidos no eletrodo de gota de mercúrio no tampão universal Britton-Robinson com valores de pH de 2 a 11 contendo 20% (v/v) de etanol exibiram um único pico catódico irreversível de 4-elétrons, correspondendo à redução de seu grupo NO 2 para hidroxilamina. Observou-se que a nitazoxanida adsorve na superfície do eletrodo de mercúrio numa monocamada com cobe...
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Direct current polarography and differential pulse polarographic methods have been developed for the qualitative as well as quantitative analysis of vitamin B1, B2 and B6. Thiamin (vitamin B1) produced a well-defined wave in 0.1 M KCl at pH 5.2 with E(1/2)=-1.2 V and E(p)=-1.22 V versus saturated calomal electrode (SCE). Riboflavin (vitamin B2) gave two distinct waves in Britton Robinson buffer...
متن کاملSimultaneous RPHPLC Determination of Nitazoxanide and Ofloxacin in Combined Tablet Dosage Form
A simple, precise, accurate, rapid and reproducible reverse phase high performance liquid chromatographic procedure was developed for simultaneous determination of nitazoxanide and ofloxacin in tablet dosage form at a single wavelength. The mobile phase used was a combination of acetonitrile:0.25M potassium dihydrogen phosphate buffer (80:20) with 0.5%v/v of triethylamine and the pH was adjuste...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2011
ISSN: 0250-474X
DOI: 10.4103/0250-474x.99022